Simple Promise · Dietary Supplements
Cholibrium
Ten mushroom extracts in one capsule, for everyday heart support.
What Cholibrium is, the ten mushrooms in the formula, how to take it, the 365-day empty-bottle guarantee, and why it is not a replacement for cholesterol medicine.
- Ten mushroom extracts
- Made in a cGMP-certified facility
- Non-GMO and gluten-free
- Free US shipping
- Independent overview
- Opens the official store
- Terms are set by the seller
Last reviewed by the Wellness Center USA editorial team
- Mushroom extracts
- 10
- Capsules a day
- 2
- Money-back guarantee
- 365-day
- Certified facility
- cGMP
The idea behind it
Heart support from the forest floor.
Cholibrium is built around mushrooms long used in food and traditional medicine. Here is how the brand frames it, with its claims kept as the brand's claims.
Ten mushrooms
Culinary favourites such as shiitake and maitake, alongside traditional ones such as reishi and chaga.
Healthy-range support
The brand says it helps maintain cholesterol levels that are already healthy — not lower high ones.
Beta-glucans
Many of these mushrooms contain beta-glucans, a fibre found in mushroom cell walls.
Before meals
Two capsules a day, 20–30 minutes before a meal with a glass of water.
“Designed to support healthy heart function and help maintain cholesterol levels already within a healthy range.”
Approach, compared
A statin, a single mushroom, or a ten-mushroom blend?
How Cholibrium's approach sits next to other options. The Cholibrium column reflects the brand's own description.
- Prescribed statin
Medical treatment
- Prescribed for high cholesterol
- Proven in large trials
- Monitored by your doctor
- Single mushroom capsule
One extract
- Usually reishi or lion's mane
- Narrow focus
- Dose on the label
- Cholibrium
Ten-mushroom blend
- For cholesterol already in a healthy range
- Non-GMO and gluten-free, per the brand
- Two capsules before a meal
- 365-day guarantee
What's inside
Ten mushrooms, grouped by tradition.
The mushroom extracts Cholibrium lists on its official site. Amounts are not published.
- Culinary
Shiitake, maitake and white button
Familiar culinary mushrooms. Shiitake and maitake are among the most studied for heart and metabolic health, mostly in early research.
- Traditional
Reishi, chaga and turkey tail
Traditional medicinal mushrooms. Reishi may affect blood clotting, so ask your doctor if you take blood thinners.
- Functional
Lion's mane and cordyceps
Lion's mane is being researched for brain health; cordyceps for energy. Both are popular functional mushrooms.
- Less common
Royal agaricus and black fungus
Royal agaricus (Agaricus blazei) and black fungus, also called tree ear or wood ear, a staple of East Asian cooking.
Cholibrium by the numbers
- Capsules per bottle
- 60
- Mushroom extracts
- 10
- US shipping on every order
- Free
- Days to request a refund
- 365
Side by side
How Cholibrium compares.
The Cholibrium column comes from the official website. The second column describes a typical single-mushroom supplement in general, not any specific product.
| Feature | Cholibrium | Typical single-mushroom capsule |
|---|---|---|
| Number of mushrooms | 10 | 1 |
| Culinary and medicinal mushrooms | Yes | Varies |
| Made in a cGMP-certified facility | Yes | Varies |
| Non-GMO, gluten-free, allergen-free | Yes, (per the brand) | Varies |
| Amounts per mushroom published | No | Yes |
| Free US shipping | Yes | Varies |
| Money-back guarantee | Yes, (365 days) | Varies |
✓ = present according to the brand · ✗ = not present · Varies = depends on the product.
Want to check current availability and details?
Visit the official Simple Promise websiteImportant
Cholesterol medicine and safety
Keep these points in mind before taking Cholibrium:
- Don't replace prescribed medicine. If you take a statin or other cholesterol medicine, keep taking it. The brand itself says Cholibrium is for cholesterol already in a healthy range.
- Blood thinners. Reishi may affect blood clotting — ask your doctor first.
- Mushroom allergy. Avoid it if you are allergic to mushrooms.
- Know your numbers. A simple blood test is the only way to know your cholesterol level.
The evidence
What we know — and don't — about Cholibrium
We found no published clinical trial of Cholibrium itself.
Cholibrium's site describes a ten-mushroom formula for heart health, but it does not publish trials of the finished product or the amount of each mushroom. Without the amounts, it is not possible to compare its doses with those used in research.
Mushrooms such as shiitake and maitake contain beta-glucans and other compounds that researchers are studying for cholesterol and metabolic health, but most of that research is in animals or small human studies, with mixed results. Mushroom supplements are not an established way to lower cholesterol. By contrast, statins and other prescribed medicines have strong evidence from large trials, and diet and exercise remain the foundation.
In plain terms: Cholibrium is a broad mushroom supplement with sensible, modest wording about cholesterol, but its heart benefits are the brand's own claims. The 365-day guarantee gives a long time to decide whether it suits you.
Good to know
Proven habits for healthy cholesterol
The approaches with the strongest evidence for heart health are everyday ones:
- More fibre — oats, beans, lentils, vegetables and fruit.
- Healthier fats — swap butter and fatty meats for olive oil, nuts and fish.
- Regular activity — at least 150 minutes a week of moderate exercise.
- Don't smoke, and keep alcohol moderate.
- Regular check-ups for cholesterol and blood pressure.
Simple routine
Getting started with Cholibrium.
Check your cholesterol with your doctor, and keep taking any prescribed medicine.
Take two capsules a day, 20–30 minutes before a meal with an 8 oz glass of water.
Keep your empty bottles — the 365-day guarantee asks for them back.
Refund policy
What the 365-day guarantee says.
Cholibrium comes with a 365 Day Money Back Guarantee: return your empty bottles within 365 days of purchase for a no-questions-asked refund. These are the seller's terms as published, not a guarantee from us.
- 365 days from purchase
- Return empty bottles
- No questions asked, per the brand
- Free US shipping on every order
Is it right for you?
Questions to ask before buying.
- Do you know your cholesterol numbers from a recent blood test?
- Do you take a statin or other cholesterol medicine? Keep taking it.
- Do you take blood thinners? Ask about reishi first.
- Are you allergic to mushrooms?
- Are you comfortable that the amount of each mushroom is not published?
- Have you noted the guarantee — 365 days, empty bottles back?
Ordering
Buying, shipping and the official site.
Cholibrium is sold through the Simple Promise official website, with ClickBank — based in Boise, Idaho — acting as the retailer. Every order includes free US shipping.
Support. Simple Promise offers product support through its help desk and a toll-free phone line, and ClickBank provides order support by phone.
Testimonials. The site notes that its testimonials are real customer reactions with names changed, and that individual results may vary.
Specifications
Cholibrium at a glance
As published on the official website. Details the site does not give are marked as not stated.
- Product
- Cholibrium™
- Brand
- Simple Promise™
- Form
- Capsules
- Suggested use
- 2 capsules daily, 20–30 minutes before a meal, with 8 oz water
- Mushrooms
- Reishi, lion's mane, cordyceps, shiitake, maitake, turkey tail, chaga, royal agaricus, white button, black fungus
- Amounts
- Not stated
- Capsules per bottle
- 60 (30-day supply)
- Manufacturing
- cGMP-certified facility
- Formula
- Non-GMO, allergen-free, gluten-free, gut-friendly (per the brand)
- Refund window
- 365 days, empty bottles
- Shipping
- Free US shipping on every order
- Retailer
- ClickBank
At a glance
Key features
Ten mushroom extracts
Including shiitake, maitake, reishi, lion's mane and turkey tail.
Made in a cGMP-certified facility
As stated on the official website.
Non-GMO and gluten-free
Also described as allergen-free and gut-friendly by the brand.
Free US shipping
On every order, according to the site.
365-day money-back guarantee
Return empty bottles for a no-questions-asked refund, per the seller.
What it's made of
Ingredients & materials
- Culinary mushrooms
- Shiitake, maitake, white button, royal agaricus and black fungus (tree ear).
- Medicinal and functional mushrooms
- Reishi (lingzhi), lion's mane, cordyceps, turkey tail and chaga. Amounts are not published.
The details
Overview
Cholibrium™ is a capsule supplement from the Simple Promise™ brand, sold through its official website. The brand says it is "designed to support healthy heart function and help maintain cholesterol levels already within a healthy range," and describes it as a formula of "10 mushroom extracts." The ten mushrooms are reishi, lion's mane, cordyceps, shiitake, maitake, turkey tail, chaga, royal agaricus, white button and black fungus (tree ear). The amounts are not published. You take two capsules a day before a meal, and each bottle holds 60 capsules — a 30-day supply. This page sets out what the official site states, how Cholibrium is meant to be taken, and what is worth knowing about mushroom supplements and cholesterol. It is an editorial overview, not a hands-on test, and nothing here is medical advice.
How it works
Cholibrium combines culinary and traditional medicinal mushrooms in a single capsule. Many of these mushrooms — shiitake, maitake, reishi and others — contain beta-glucans, a type of fibre found in mushroom cell walls, along with other plant compounds that researchers are studying for heart and metabolic health. The brand's wording is careful: it says Cholibrium helps maintain cholesterol levels that are already within a healthy range. It does not publish clinical trials of the finished formula or the amount of each mushroom, so how well the combination works has not been independently shown. It is not designed to lower high cholesterol, and it is not a substitute for prescribed treatment.
Who it's for
Cholibrium is marketed to adults whose cholesterol is already in a healthy range and who want a daily mushroom supplement as part of looking after their heart. The brand describes it as non-GMO, allergen-free, gluten-free and gut-friendly. It is not a treatment for high cholesterol or heart disease. If you have been prescribed a statin or other cholesterol medicine, keep taking it — never stop or change prescribed medicine on your own. People with a mushroom allergy should avoid it, and anyone on blood thinners should ask their doctor first, as reishi may affect blood clotting.
Usage
The official site says to take two capsules daily, preferably 20–30 minutes before a meal with an 8 oz glass of water, or as your healthcare provider recommends. Speak to your doctor first if you take medication — especially blood thinners, blood-pressure or diabetes medicine — are pregnant or nursing, or have a medical condition.
Common questions
Frequently asked questions
What is Cholibrium?
Cholibrium is a ten-mushroom capsule from the Simple Promise brand, marketed to support heart function and help maintain cholesterol levels already within a healthy range.
What mushrooms are in Cholibrium?
Reishi, lion's mane, cordyceps, shiitake, maitake, turkey tail, chaga, royal agaricus, white button and black fungus. Amounts are not published.
How do I take Cholibrium?
Two capsules daily, preferably 20–30 minutes before a meal with an 8 oz glass of water, or as your healthcare provider recommends.
Can Cholibrium lower high cholesterol?
The brand says it supports cholesterol already in a healthy range; it is not presented as a treatment for high cholesterol. Talk to your doctor about proven options.
Can I stop my statin if I take Cholibrium?
No. Never stop or change prescribed medicine without talking to your doctor.
Is Cholibrium safe with blood thinners?
Ask your doctor first. Reishi may affect blood clotting.
Has Cholibrium been clinically tested?
We found no published trial of Cholibrium itself, and the site states its statements have not been evaluated by the FDA.
What is the Cholibrium guarantee?
A 365-day money-back guarantee: return your empty bottles within 365 days of purchase for a no-questions-asked refund.
How many capsules are in a bottle?
60 capsules, a 30-day supply at two capsules a day.
Is shipping free?
Yes — the site says every order gets free US shipping.
Who makes Cholibrium?
It is sold under the Simple Promise brand, with ClickBank as the retailer. Simple Promise offers phone and help-desk support.
What are beta-glucans?
A type of fibre found in the cell walls of mushrooms, oats and barley. Oat beta-glucan has good evidence for cholesterol; mushroom beta-glucans are still being studied.
Why take it before a meal?
The site recommends 20–30 minutes before a meal with water. It does not explain why, so follow the label or your healthcare provider's advice.
Is Cholibrium vegan?
The site describes it as allergen-free, gluten-free and non-GMO but does not say whether the capsule shell is plant-based. Check the label.
Where should I buy Cholibrium?
From the official website, where ClickBank processes the order. Buying there keeps the 365-day guarantee in place.
Before you go
What happens when you click the button?
You go to the official store
The button opens the seller's official page. This site never takes your payment details.
Check the details there
Price, availability, shipping and the guarantee are set by the seller and can change, so confirm them before you order.
The seller handles your order
Checkout, delivery and any refund request go through the seller and its customer support, not through us.
See Cholibrium on the official site.
Prices, availability and current return terms are set by the seller and can change — check them on the official site before you buy.
Clinical reviewer
James Willson, PharmD
Clinical Pharmacist · Health content reviewer · Six years’ professional experience
James Willson is a clinical pharmacist with a Doctor of Pharmacy (PharmD) qualification and six years of professional experience in clinical pharmacy and the review of health-related information.
He reviews health and wellness content on Wellness Center USA for accuracy, clarity, appropriate terminology and responsible presentation of product information — including ingredient details, usage instructions, precautions and references to scientific research, where applicable.
His goal is to help readers understand health and wellness information clearly, tell product claims apart from established evidence, and make better-informed decisions.
Editorial note
Information on this page reflects manufacturer statements, which are attributed as such, and our own research. It is provided for informational purposes and is not medical advice.
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